THE EFFECTS OF "HOI XUAN HOAN" CAPSULES ON SPERM COLLECTION EFFICIENCY AND MORPHOLOGICAL SPERM STRUCTURE OBTAINED BY MICRO IN NONOBSTRUCTIVE AZOOSPERMIA PATIENTS

Abstract

SUMMARY Objectives: To evaluate the efficiency of sperm collection and describe the characteristics of

sperm structure obtained from microdissection testicular sperm extraction (micro tese) in non- obstructive azoospermia patients (NOA) after using the capsule "Hoi xuan hoan". Subjects and

methods: 88 NOA patients were divided into 2 groups: Group 1: 41 patients were treated with capsule "Hoi xuan hoan" for 3 months and group 2: 47 patients had no treatment. These patients were taken micro at the Military Clinical Embryo Institute, Vietnam Military Medical University from 5/2017 to 12/2019. Results: The rate of sperm collection by micro method was 39.77%, of which group 1 was 46.34% and group 2 was 34.04%; The sperm collection median density in group 1 was 2 million/mL higher than group 2 with 0.5 million/mL significantly (p < 0.05). The rate of alive sperm, normal morphological sperm and mobile sperm ratio in group 1 was higher than that in group 2 (p > 0.05). Conclusions: "Hoi xuan hoan" capsules helped to improve the process of spermatogenesis inside the teses, thereby increasing the density and the chance of obtaining sperm by micro in NOA patients.